Developed by AstraZeneca with FDA approval coming in 2001, Nexium (esomeprazole) has established itself as one of the United States’ top grossing drugs over the last decade.

However, this proton pump inhibitor (PPI), in following suit with the acid reflux/heartburn drugs of its class has been the subject of dozens of medical studies over the last decade that have uncovered multiple dangerous side effects that were previously unknown to medical professionals and consumers.

These side effects range from life threatening – kidney complications and dementia – to common health issues, including:

Headache Nausea
Diarrhea Abdominal Pain
Fatigue Dizziness
Dry Mouth Constipation
Flatulence Decreased Appetite


What Effect Does Nexium Have On A Users Kidney?

PPI’s were first introduced to the market in the 1990’s and garnered immense popularity as an effective heart burn treatment medication.

However, in the past two decades, extensive studies have been conducted on PPI’s including Nexium and their effect on consumers kidneys.

One of the most documented studies conducted on PPI’s was published in February 2015.

The study, which was conducted by professors residing at Washington University in St. Louis determined that there was a 28% increased risk of kidney damage in PPI users in addition to a 98% increased risk of kidney failure.

Those who took PPI’s were medically compared to H2 users over a course of five years.

A study conducted by researchers based at Johns Hopkins University and another published in JAMA Internal Medicine yielded similar results.

This has provided enough medical evidence for consumers and medical professionals to take note of this possible health risk and begin filing lawsuits against AstraZeneca.

It is important to understand however, these studies do not offer conclusive evidence of a causation relationship between Nexium and kidney complications. Rather, they offer a credible evidential base to begin the exploratory phase of your legal process.

The side effects noted by the aforementioned studies that can be associated with extended PPI use include:

  • Chronic Kidney Disease (CKD): Gradual loss of kidney function
  • Acute Kidney Injury (AKI): Kidney complications occurring within hours or days
  • Interstitial Nephritis: Inflammation off kidneys

Additional information regarding published studies and kidney complications as they relate to PPI use can be found here.

How Dangerous Are Nexium Kidney Complications To Consumers?

Any kidney complication has the potential to be life threatening if not appropriately treated by a qualified medical professional.

In the event of AKI, a victim can quickly develop chronic kidney disease or complete kidney failure.

Chronic kidney disease is often difficult to detect until it has progressed into an advanced stage, but if discovered, it may be characterized by:

  • Fatigue
  • Lack of Concentration
  • Loss of Appetite 
  • Difficulty Sleeping
  • Nighttime Muscle Cramping
  • Swelling of the Feet and Ankles
  • Puffiness of the Eyes
  • Development of Dry or Itchy Skin
  • Urinating More Often

It is especially difficult to detect CKD as kidneys are extremely adaptive and compensate for damage until the damage has become so severe that it may be irreparable.

If CKD is allowed to develop for a long enough time, it may develop into the most dangerous kidney condition – end-stage renal disease (ESRD).

This condition is characterized by a complete halt in kidney function leading to your body filling with extra water and waste products – a uremia.

Swelling may often occur in extremities with extreme fatigue and weakness quickly developing.

When ESRD is left untreated, victims begin suffering from seizures or may fall into a coma. These side effects have the potential to cause death in those afflicted.

For this reason, even conservative estimates of how PPI’s effect kidneys are cause for major concern.

Has The FDA Issued A Drug Recall For Nexium?

As of June 2016, neither the U.S. Food and Drug Administration nor AstraZeneca has issued a recall of Nexium or indicated that one is imminent.

While dozens of studies over the decade have resulted in data supporting the claim that PPI’s, including Nexium, often lead to increasing the risk of kidney complications in consumers, the FDA has continued to maintain a stance of monitoring the situation rather than taking acting against AstraZeneca.

However, after being sued by Public Citizen, INC. in the United States District Court for the District of Columbia alleging that a lack of action has constituted a violation of procedure, the FDA has made greater attempts to inform the public of the possibility of kidney damage in consumers.

Our Nexium Kidney Injury Lawyers Can Help You

Our dangerous prescription and over-the-counter drug lawyers can help you if you or someone you love has been diagnosed with serious kidney complications after taking Nexium. Lawsuits are expected to be filed against the makers of this medication. You may be entitled to a Nexium settlement.

Our No Fee Promise on Nexium Cases

You can afford to have our great team of Nexium lawyers on your side. When you choose us, it literally costs nothing to get started. We promise you in writing:

  • No money to get started
  • We pay all case costs and expenses
  • No legal fees unless you receive a Nexium settlement
  • Phone calls are always free

Start Your Nexium Claim

Our Nexium lawyers will help you file your lawsuit. To get started, you can:

  1. Submit the Free Case Review Box on this page, or
  2. Call (866) 280-3417 any time of day to tell us about your case.

We will listen to your story and answer your questions. If you have claim, we will start immediately.

WARNING: There are strict time deadlines for filing Nexium lawsuit claims.