Aciphex Lawsuits: Kidney Complications
Commonly asked questions about Aciphex (rabeprazole):
- What is Aciphex?
- How does gastroesophageal reflux disease (GERD) occur?
- What are common acid reflux symptoms?
- How can it be administered?
- What are common health complications?
- What are serious side effects?
- Has Aciphex been linked to chronic kidney disease (CKD)?
- Am I eligible to file a lawsuit?
- How do I start a claim?
What Is Aciphex?
One of the major drugs constituting the proton-pump inhibitor class, it was developed to treat symptoms of frequent heartburn caused by acid reflux. It does so by preventing the backup of stomach acid and/or bile into the esophagus which in serious cases can lead to extensive damage.
Aciphex is manufactured by Japanese pharmaceutical company, Eisai Co., Ltd. and was approved by the U.S. Food and Drug Administration in 2002. Since approval, the anti-ulcer drug has become one of the most popular proton-pump inhibitor drugs on the market and is regularly a top 100 yearly selling drug.
The drug – which is in the same pharmacologic class of drug as omeprazole – allows the esophagus to heal from the effects of acid reflux by decreasing the stomachs ability to make acid. If taken early enough, the drug can prevent the development of ulcers (sores in stomach or esophagus lining) and nonsteroidal anti-inflammatory drug-induced ulcers.
The drug can be prescribed in two forms, a delayed-release tablet or a delayed-released capsule referred to as “Aciphex Sprinkle.” Delayed-release tablets are swallowed whole as a standard pill while Aciphex Sprinkle is administered by sprinkling the opened capsule over a food or liquid to be consumed.
In addition to being prescribed to combat symptoms of heartburn and acid reflux, it can be used to treat symptoms similar to Zollinger-Ellison syndrome in which the stomach produces too much acid.
As a drug class proton pump inhibitors routinely rank as one of the most prescribed type of drugs with reported sales indicating 15 million individual prescriptions to Americans per year. However, while these drugs are immensely popular there have been multiple complications discovered to be associated with use PPI drugs.
PPI popularity has led to dozens of studies being conducted to discover what the true effects of extended drug use may be. These studies have yielded shocking data in the previous two years as results have indicated a strong connection between PPI use and chronic kidney disease (CKD).
With health complications associated with PPI drugs occurring in increasing numbers, dangerous drug attorneys are actively investigating lawsuits for PPI victims who suffered from health complications associated with their drug prescription.
How Does Gastroesophageal Reflux Disease (GERD) Occur?
Acid reflux is a common medical condition that can occur in a wide range of demographics including healthy infants, children, and adults. While common, they typically occur in brief spurts with no life-altering symptoms or painful complications.
There are several common causes of acid reflux disease with one of the most common being a stomach abnormality called hiatal hernia. Just as acid reflux, hiatal hernias can occur in people of any age and any health.
The most commonly reported cause of acid reflux disease is an issue plaguing the lower esophageal sphincter (LES) muscle. The LES serves as a barrier between the stomach and esophagus, closing tightly between the two organs after food has passed through to the stomach.
In sufferers of acid reflux disease, the LES is unable to close tight enough to form an impregnable barrier between the stomach and esophagus. With no barrier present between the two organs, stomach acid is able to flow into the esophagus causing intense pain and burning sensations.
In addition to pain and burning sensations, acid reflux can cause pain the upper abdomen and chest, nausea, bloating, and indigestion (dyspepsia). While these symptoms typically occur briefly without intense pain, they can develop into painful symptoms with a peak after meals.
What Are Common Acid Reflux Symptoms?
In order to be diagnosed with acid reflux disease, a victim needs to contact a doctor after experiencing and identifying a symptom associated with the disease. These symptoms routinely include the following:
|Bloody or black stools||Bloody vomit|
|Chronic sore throat||Wheezing, hoarseness|
How Can Aciphex Be Administered?
Aciphex is available to as a delayed-release tablets and as a delayed-released oral suspension capsule – Aciphex Sprinkle – and are available in 20 mg doses. The drugs should not be altered in any way, only being swallowed or inserted into food as detailed and never being crushed, split, or chewed. Unless otherwise instructed by a doctor, it should be taken once per day (24 hours).
- Open capsule
- Sprinkle contents on small amount of food (applesauce, fruit, yogurt, etc.) or small amount of liquid (apple juice, etc.)
- Full contents of capsule should be consumed within 15 minutes of capsule opening
- Mixture should be at or below room temperature and never stored for future use
Aciphex Delayed-Release Tablet
- Swallow tablet whole
- Never chew, crush, or split tablet
- Tablet can be taken with or without food depending on patient preference
What Should I Tell My Doctor Before Being Prescribed Aciphex?
In order to ensure that you are not exposing yourself to major health risks, it is important to disclose if you have suffered from the following health issues or will expose yourself to one of the following risk factors:
- Suffered from low magnesium levels in your blood
- Liver problems
- Are pregnant or planning to become pregnant (Effects of Aciphex on newborns unknown)
- Are breastfeeding (Unknown of Aciphex passes through breast milk)
Tell A Doctor If You Are Taking The Following Medications:
- Atazanavir (Reyataz)
- Cyclosporine (Sandimmune, Neoral)
- Digoxin (Lanoxin)
- Ketoconazole (Nizoral)
- Warfarin (Coumadin)
- Theophylline (THEO-24 Thelair)
- Diazepam (Valium)
- Phenytoin (Dilantin)
- Antibiotic Containing Amoxicillin or Clarithromycin
- A “Water Pill” (Diuretic)
- Mycophenolate Mofetil (Cellcept)
What Are Common Aciphex Health Complications?
Like most medications, as more reports are made public, more side effects associated with drug use is being discovered. Some of the most common side effects associated with Aciphex use include:
What Are Serious Aciphex Side Effects?
|Face Swelling||Throat Tightness|
|Difficulty Breathing||Abdomen Pain|
Has Aciphex Been Linked To Chronic Kidney Disease (CKD)?
Several studies have been published in recent years indicating a strong link between proton pump inhibitors and the development of long-term kidney damage.
One of the most widely distributed studies was published in the JAMA Internal Medicine Journal on January 11, 2016 by a group of researchers based at Johns Hopkins University in Baltimore.
The study indicated that proton pump inhibitor users are at a 20% to 50% higher risk of developing chronic kidney disease than those who do not use PPI drugs.
“We found there was an increasing risk associated with an increasing dose,” lead author Dr. Morgan Grams, an assistant professor of epidemiology at Johns Hopkins University, told HealthDay. “That suggests that perhaps this observed effect is real.”
Dr. Gram indicated that use of PPI drugs was already acknowledged to be related to short-term kidney problems, including acute kidney injury and an inflammatory disease call acute interstitial nephritis.
However, the study intended to determine if PPI use can be associated with long-term kidney failure in drug users. The study focused on 322 PPI users and yielded a 10-year estimate for the absolute risk of chronic kidney disease of 11.8%.
The results from the Johns Hopkins study and subsequent studies has confirmed many fears that PPI use is frequently associated with chronic kidney disease. If it progresses far enough, chronic kidney disease can lead to kidney failure resulting in a patient needing regular dialysis treatments and possibly a kidney transplant.
Am I Eligible To File An Aciphex Lawsuit?
With severe kidney complications now being widely reported in users of PPI drugs, previous patients are seeking ways to receive compensation for the damages incurred.
To determine if you are eligible to file a lawsuit, an attorney will work to meet the set list of criteria points that constitute an effective lawsuit. The necessary steps leading up to filing a lawsuit includes:
- Collecting All Medical Records
- Conduct A Thorough Medical Record Examination
- Prove Medical Complications Occurred In Necessary Timeline
Our No-Fee Promise on Kidney Disease Cases
You can afford to have our great team of lawyers on your side. If you choose us, it literally costs you nothing to get started. We promise you in writing:
- No money to get started
- We pay all case costs and expenses
- No legal fees whatsoever unless you receive a Aciphex settlement
- Phone calls are always free
How Do I Start An Aciphex Claim?
Our lawyers will help you file your lawsuit. To get started, you can:
- Submit the Free Case Review Box on this page, or
- Call (866) 280-3417 any time of day to tell us about your case.
We will listen to your story and answer your questions. If you have claim, we will start immediately.
WARNING: There are strict time deadlines for filing Aciphex lawsuit claims.