Zegerid Drug Lawsuit Source

Zegerid Lawsuits: Kidney Complications

Commonly asked questions about Zegerid (omeprazole):

What Is Zegerid?

Zegerid is one of the major drugs that constitute the proton pump inhibitor (PPI) drug class designed to combat the symptoms of frequent heartburn caused by the flow of stomach acid into the esophagus – acid reflux.

The drug is available to consumers as a standard capsule and a powder for oral suspension, each taken by mouth. The chemical makeup of both methods works by decreasing the amount of acid the stomach is able to produce, giving the esophagus time to heal from previous acid damage. This healing time allows the body to prevent or halt the development of ulcers – sores in the lining of the stomach or intestine.

Developed by pharmaceutical giant Bayer AG, Zegerid was first approved by the U.S. Food and Drug Administration in 2004 for both methods of use. While being approved primarily to combat the symptoms of acid reflux, the drug is also approved for use for conditions in which the stomach produces too much acid – Zollinger-Ellison syndrome.

Proton pump inhibitor drugs routinely rank as one of the most popular drug types with over 15 million PPI prescriptions issued to Americans each year. The drugs immense popularity has led to it becoming the subject of dozens of medical studies to discover possible health risks associated with prolonged drug use.

These studies have published concerning results for Zegerid consumers and medical professionals as they have indicated a strong connection between Zegerid use and the development of chronic kidney disease. If able to develop into late stages, chronic kidney disease prevents the kidneys from filtering blood effectively and can result in organ failure.

With the consumer risk growing, dangerous drug attorneys are investigating the possibility of filing lawsuit against drug manufacturers to win justice on behalf of consumers who have suffered from Zegerid related health symptoms.

What are the Criteria for Filing a Proton Pump Inhibitor Lawsuit?

Proton pump inhibitors (PPIs) were introduced in the late 1980s for the treatment of acid-related disorder of the upper gastrointestinal tract, including peptic ulcers and gastrointestinal reflux disorders, and are available both as prescription and over-the-counter drugs.

Drug Lawsuit Source is currently investigating PPI-induced Acute Interstitial Nephritis (AIN), which is a condition where the spaces between the tubules of the kidney cells become inflamed. The injury appears to be more profound in individuals older than 60.

While individuals who suffer from AIN can recover, most will suffer from some level of permanent kidney function loss. In rare cases individuals suffering from PPI-induced AIN will require kidney transplant.

Our top-rated lawyers are handling individual litigation nationwide and currently accepting new Proton Pump Inhibitor cases in all 50 states. Below is the criteria required for filing a proton pump inhibitor lawsuit:

  • Patient took one of the following PPIs by prescription or over-the-counter for at least one year:
    • Nexium
    • Prilosec
    • Dexilant
    • Prevacid
    • Protonix
    • Aciphex
    • Zegerid
  • Patient diagnosed with new onset of one of the following while taking the PPI:
    • Acute kidney/renal failure
    • Chronic kidney/renal disease
    • Acute interstitial nephritis

Both patients and their families are seeking compensation for damages. You may be entitled to a settlement if you were harmed by PPI’s.

How Did I Get Gastroesophageal Reflux Disease (GERD)?

Anyone is able to suffer from acid reflux disease as it can be a naturally occurring condition that effects healthy infants, children, and adults regardless of pre-existing conditions. While the condition is common, most episodes of it are fast and do not carry debilitating symptoms or complications.

Hiatel hernias are commonly cited as one of the most common causes of acid reflux disease.

However, the most common cause of acid reflux disease is the development of a problem relating to the function of the lower esophageal sphincter (LES) muscle. The LES muscle serves as a “valve” between the stomach and esophagus, preventing stomach acid from seeping into the esophagus.

The “valve” opens as food passes through the esophagus to the stomach and closes once all the contents have been transported out of the esophagus. However, if the LES muscle is unable to close as it is designed to do, acid will be able to move freely between the two organs.

With the esophagus not designed to withstand stomach acid, the introduction of the acid can cause discomfort and painful burning sensations. Other symptoms may include pain in the chest, bloating, and indigestion which typically peak in intensity after a meal.

What Are The Symptoms Of Acid Reflux?

While the symptoms of acid reflux typically do not endure for an extended period of time, they can cause significant discomfort in a consumer. These health symptoms include:

Heartburn Bloating
Bloody or black stools Bloody vomit
Fatigue Dizziness
Burping Dysphagia
Nausea Weight loss
Chronic sore throat Wheezing, hoarseness


How Do I Take Zegerid?

Zegerid is available in the two standard methods in which most PPI drugs are available in. These methods are the standard capsule and a powder for oral suspension and are available in 20 mg or 40 mg strength. Unless otherwise instructed by a doctor, the drug should be taken once daily (per 24 hours) for between four and eight weeks.

How Do I Take A Zegerid Capsule?

  • Capsules should be swallowed intact with water
  • No other liquids should be used when swallowing Zegerid
  • Capsules should not be opened and contents should not be sprinkled
  • Capsules should not be altered or manipulated in any way
  • Entire capsule must be taken, drug should not be rationed for later use

How Do I Take Zegerid Oral Suspension?

  • Empty packets of contents into 1-2 tablespoons of water
  • No other liquids or foods should come in contact with Zegerid
  • Stir mixture and immediately drink
  • Refill cup and swallow until all contents have been administered
  • Contents should not be ration, take entire dosage

Tell Your Doctor Before Taking Zegerid If You Have/Are:

  • Been told you have low magnesium, calcium, or potassium blood levels
  • Liver problems
  • Heart failure
  • Bartter’s syndrome
  • Allergies
  • Pregnant or plan to become pregnant
  • Breastfeeding or plan to breastfeed

Tell Your Doctors If You Take The Following Medicines:

  • Mycophenolate mofetil (Cellcept)
  • Diazepam (Valium®)
  • Warfarin (Coumadin®, Jantoven)
  • Phenytoin (Dilantin®)
  • Cyclosporine (Gengraf, Neoral, Sandimmune)
  • Disulfiram (Antabuse®)
  • A benzodiazepine medicine
  • Ketoconazole (Nizoral®)
  • An antibiotic that contains ampicillin
  • Products that contain iron
  • Digoxin (Lanoxin®)
  • Voriconazole (Vfend®)
  • Atazanavir (Reyataz®)
  • Nelfinavir (Viracept®)
  • Tacrolimus (Prograf®)
  • Saquinavir (Fortovase®)
  • Clarithromycin (Biaxin®, Biaxin XL)
  • Clopidogrel (Plavix®)
  • St. John’s Wort (Hypericum perforatum)
  • Rifampin (Rifater, Rifamate, Rimactane, Rifadin)
  • Methotrexate

What Are The Most Common Zegerid Side Effects?

As Zegerid has been exposed to the market for longer periods of time, more side effects associated with the drug use have been discovered to afflict consumers. The most common of these side effects include:

Headache Diarrhea
Abdominal Pain Nausea
URI Dizziness


What Are Additional Zegerid Side Effects?

In addition to the aforementioned common side effects, Zegerid reportedly causes the following conditions among others:

Rash Constipation
Cough Asthenia
Back Pain Flatulence


Does Zegerid Cause Chronic Kidney Disease (CKD)?

A recent study conducted by researchers at Johns Hopkins University at Baltimore was published on January 11, 2016 in the JAMA Internal Medicine Journal. The study contained data the heavily suggested that Zegerid, in addition to other proton pump inhibitors, may be linked to long-term kidney damage.

“We found there was an increasing risk associated with an increasing dose,” lead author and assistant professor of epidemiology at Johns Hopkins University, Dr. Morgan Gram told HealthDay. “That suggests that perhaps this observed effect is real.”

The study reported that proton pump inhibitor users were 20% to 50% more likely to develop chronic kidney disease compared to nonusers. These figures were gathered from observing 322 PPI users who were estimated to have a 10-year absolute risk for chronic kidney disease of 11.8%.

While Dr. Gram acknowledged that an association between PPI use and short-term kidney problems have been known previously, but new studies mark the first time long-term kidney failure type complications have been connected to PPI use.

The long-term kidney effects detailed in the study can develop so severely that consumers may need to undergo dialysis treatments or a kidney transplant, according to the U.S. National Institutes of Health.

Our No-Fee Promise on Zegerid Kidney Disease Cases

You can afford to have our great team of Zegerid lawyers on your side. If you choose us, it literally costs you nothing to get started. We promise you in writing:

  • No money to get started
  • We pay all case costs and expenses
  • No legal fees whatsoever unless you receive a Zegerid settlement
  • Phone calls are always free

How Can I File A Zegerid Kidney Disease Claim?

Our Zegerid lawyers will help you file your lawsuit. To get started, you can:

  1. Submit the Free Case Review Box on this page, or
  2. Call (866) 280-3417 any time of day to tell us about your case.

We will listen to your story and answer your questions. If you have claim, we will start immediately.

WARNING: There are strict time deadlines for filing Zegerid lawsuit claims.

View Sources

  1. Prescribing Information – FDA
  2. Medication Guide – FDA
  3. Approval Letter(s) – FDA