MONTREAL — A recent study has uncovered additional evidence linking the diabetes drug Actos to an increased risk of bladder cancer.

Actos (pioglitazone) appears to increase risk of bladder cancer by 63 percent, according to Canadian researchers. The study, which was published March 30, analyzed nearly 146,000 patients treated between 2000 and 2013.

The data showed an increased risk of being diagnosed with bladder cancer among patients who used Actos for more than two years — or if someone takes more than 28,000 milligrams over the course of their lives.

Senior researcher Laurent Azoulay, an associate professor of oncology at McGill University in Montreal, said the overall risk was small, but “the more you accumulate the drug into your system, the higher the risk.”

The maker of Actos, Takeda Pharmaceuticals, issued a statement in response to the study.

“Takeda is confident in the positive benefit-to-risk profile of pioglitazone. Two large, long-term observational studies found no significant increase in the risk of bladder cancer in diabetic patients taking pioglitazone. This data includes a 10-year, prospective cohort study, conducted by the University of Pennsylvania and Kaiser Permanente Northern California and … a large epidemiological study utilizing five European Union databases … to investigate the potential risk of bladder cancer with pioglitazone use,” said Elissa Johnsen, head of the company’s Global Product and Pipeline Communications.

Actos use has dropped sharply in the past several years (from 20 percent of anti-diabetes drug prescriptions in 2008 to seven percent in 2013), partially because the Food and Drug Administration affixed a “black box” warning to its label.

Discovery Rule in Actos Cases

The exact statute of limitations to bring a claim varies by state. In negligence cases, it is generally two years. But the limitations period is not always 730 days. The limitations period is “tolled,” which means the clock stops ticking, until the plaintiff knows about the injury and knows about the possible negligence that could have caused the injury. Consider the following hypothetical timeline:

  • 2011 – Patient begins taking Actos
  • 2013 – Patient starts experiencing bladder cancer symptoms, but is not diagnosed
  • 2014 – Patient is diagnosed with bladder cancer
  • 2015 – The FDA changes the warning label to reflect the known link between Actos and bladder cancer, but since the patient is no longer taking the medicine, the patient does not actually know about the change
  • 2016 – Patient sees a lawyer’s television commercial advising viewers of the risks of Actos

Arguably, any one of these events could be a trigger that starts or stops the statute of limitations clock. The bottom line is that, if you or a loved one was injured while ingesting a dangerous drug, time is not on your side.

Our Actos Lawyers Can Help

Our dangerous drug attorneys can help if you or someone you care about was injured during or after ingesting Actos. Lawsuits have been filed against the drug makers by both patients and their families seeking compensation for injuries caused by the dangerous drug. You may be entitled to a settlement.

Our No-Fee Promise in Actos Cases

You can afford to have our great team of lawyers on your side. When you choose us, it literally costs nothing to get started. We promise you in writing:

  • No money to get started,
  • We pay all case costs and expenses,
  • No legal fees whatsoever unless you receive a settlement, and
  • Phone calls are always free.

Start Your Actos Lawsuit Claim

Our dangerous drug lawyers will help you file your lawsuit. To get started, you can:

  • Submit the Free Case Review Box on this page, or
  • Call (866) 280-4722 any time of day to tell us about your case.

We will listen to your story and answer your questions. If you have claim, we will start immediately.

WARNING: There are strict time deadlines for filing dangerous drug lawsuit claims.