The study’s findings indicate that blood vessel cells can be hindered from preventing clotting and protecting one from strokes and heart disease, shown in a study by Houston Methodist.
Taking PPI’s in the long-term have been linked to a reduction in lysosome production. Lysosomes clear waste meaning a shortage of them results in cell waste buildups — a catalyst for cell aging.
“Lysosomes are like the garbage disposal of the cells,” said cardiovascular sciences professor Dr. John P. Cooke, the lead study author.
However, the study was done in a laboratory setting, not on humans in a clinical trial, which has led the study team to encourage further long-term clinical trials to further research this possible side effect.
Because it was not a long-term human clinical trial, drug manufacturer AstraZeneca issued this statement: “Patient safety is an important priority for AstraZeneca and we believe all of our PPI medicines are generally safe and effective when used in accordance with the label.”
However, outside medical professionals say the drug should be approached with caution due to the potential complications and to focus on healthy lifestyle changes to quell heartburn before deciding to take Nexium.
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