Onglyza Drug Lawsuit Source

Onglyza & Heart Attacks: Lawsuits & Lawyers

Commonly asked questions about the link between Onglyza (saxagliptin) and heart attacks/heart failure:

Can Onglyza Cause Heart Attacks and Heart Failure?

Recent studies suggest there may be a link to dangerous side effects associated with the use of Onglyza — a popular medication among people who suffer from type 2 diabetes.

There have been reports of increased risk of heart failure and heart attacks in some patients who have been prescribed this medication.

The United States Food & Drug Administration has issued several safety communications that have specifically address Onglyza and the class of drugs it belongs to, known as DPP-4 inhibitors. In the latest safety communication released on April 5, 2016, the FDA warns that there may be an increased risk of heart failure associated with Onglyza.

Lawsuits are being investigated by our legal team for people who have suffered complications, including heart attacks, after using Onglyza. You may be able to recover compensation if you have been harmed. On the page below, you will find more information about Onglyza side effects and complications.

Attorneys are accepting lawsuits from people who suffered heart attacksheart failure, congestive heart failure, cardiac failure or death before April 5, 2016.

If you believe Onglyza has contributed to a diagnosis of heart failure or heart attack in your family, you may be entitled to file a lawsuit and recover compensation. It is important to contact an attorney as soon as possible so you can receive information and potentially receive a settlement.

Does Onglyza Increase the Risk of Heart Attacks?

In April 2016, the U.S. Food and Drug Administration announced that the agency added new warnings to Onglyza’s labels about the risk of heart failure and heart attacks.

The FDA found that type 2 diabetes medicines containing saxagliptin and alogliptin (marketed as Onglyza and Kombiglyze XR) may increase the risk of heart failure and possibly heart attacks, particularly in patients who already have heart or kidney disease.

Heart failure, which may lead to a heart attack, can result in the heart not being able to pump enough blood to meet the body’s needs.

Saxagliptin and alogliptin are part of the class of dipeptidyl peptidase-4 (DPP-4) inhibitor drugs, which are used with diet and exercise to lower blood sugar in adults with type 2 diabetes. Untreated, type 2 diabetes can lead to serious health problems, including blindness, nerve and kidney damage, and heart disease (see List of saxagliptin- and alogliptin-containing Medicines).

Can I File An Onglyza Heart Attack Lawsuit?

A recently filed lawsuit suggests drug manufacturer Bristol-Myers Squibb Company knew of potential heart-related side effects but failed to adequately warn the public and medical community.

Sanders Phillips Grossman filed a lawsuit in February 2017 in the U.S. District Court for the Southern District of Texas against Bristol-Myers Squibb Company over the companies’ alleged failure to warn consumers and the medical community of the risk of heart failure for diabetes patients using Onglyza and Kombiglyze XR.

The main defendants named in these lawsuits are Bristol-Myers Squibb, AstraZeneca and Amylin Pharmaceuticals, LLC — a wholly owned subsidiary of AstraZeneca. Among the other defendants named in the lawsuit include: IPR Pharmaceuticals and McKesson Corp. — companies that may have been involved in distribution, manufacturing and marketing of Onglyza and Kombiglyze XR.

The plaintiff, Wrendell Chester used both drugs to treat his type 2 diabetes for approximately five years between 2010-2015, after which he reportedly suffered heart failure, congestive heart failure and acute hypoxic respiratory failure — as a result of side effects of the medications.

What Are The Symptoms of a Heart Attack?

Patients taking Onglyza should contact their health care professionals right away if they develop signs and symptoms of heart failure and heart attacks such as:

Heart Failure/Heart Attack Signs & Symptoms 
Unusual shortness of breath during daily activities
Trouble breathing when lying down
Tiredness, weakness, or fatigue
Weight gain with swelling in the ankles, feet, legs, or stomach

How Many Onglyza Heart Failure Lawsuits Have Been Filed?

At this time, it is unclear if heart attack lawsuits and heart failure lawsuits against Onglyza will be filed as individual lawsuits or a class action lawsuit. In December 2016, California plaintiffs filed a motion to consolidate similar cases for pretrial in the California Superior Court.

As of February 2017, approximately 85 claims remain in active litigation, according to an annual report published by AstraZeneca.

What Are The Serious Side Effects of Onglyza?

Serious side effects associated with Onglyza include:

What Are The Less Severe Side Effects of Onglyza?

Less severe Onglyza side effects may include:

  • Allergic reactions, including: hives and swelling
  • Difficulty breathing
  • Unexplained muscle pain or weakness
  • Joint pain
  • Confusion
  • Memory problems
  • Fever
  • Unusual tiredness
  • Dark colored urine
  • Swelling
  • Weight gain
  • Urinating less than usual or not at all
  • Severe pain in the upper stomach
  • Nausea
  • Vomiting
  • Loss of appetite
  • Fast heart rate
  • Increased thirst
  • Increased urination
  • Blurred vision
  • Weight loss
  • Itching
  • Dark urine

Our Onglyza Heart Attack Lawyers Can Help

Our dangerous prescription drug lawyers can help if you or a loved one has suffered or been diagnosed with heart failure or a heart attack due to taking Onglyza. Lawsuits are being investigated for serious complications that have caused pain and suffering in many patients. You may be entitled to a settlement.

We do not charge any legal fees unless we win your case, and we will pay for all case costs and litigation expenses. If your claim in not successful for any reason, you will owe us nothing. We put that all in writing for you. We’ll help you file you’re Onglyza lawsuit.

Our No-Fee Promise on Onglyza Heart Attack Cases

You can afford to have our great team of Onglyza lawyers on your side. If you choose us, it literally costs you nothing to get started. We promise you in writing:

  • No money to get started
  • We pay all case costs and expenses
  • No legal fees whatsoever unless you receive an Onglyza settlement
  • Phone calls are always free

Start Your Onglyza Lawsuit Claim

Our Onglyza lawyers will help you file your lawsuit. To get started, you can:

  1. Submit the Free Case Review Box on this page, or
  2. Call (866) 280-4722 any time of day to tell us about your case.

We will listen to your story and answer your questions. If you have claim, we will start immediately.

WARNING: There are strict time deadlines for filing Onglyza lawsuit claims.

Onglyza Heart Attack Lawyer Review

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View Sources

  1. FDA Drug Safety Communication – U.S. Food and Drug Administration
  2. FDA to Review Heart Failure Risk – U.S. Food and Drug Administration
  3. Heart Failure, Saxagliptin and Diabetes Mellitus – American Heart Association, Inc.


  • Kannel, WB, Hjortland, M, and Castelli, WP. Role of diabetes in congestive heart failure: the Framingham study. Am J Cardiol. 1974; 34: 29–34.
  • Leung, AA, Eurich, DT, Lamb, DA et al. Risk of heart failure in patients with recent-onset type 2 diabetes: population-based cohort study. J Card Fail. 2009; 15: 152–157.
  • Prentice, RL, Williams, BJ, and Peterson, AV. On the regression analysis of multivariate failure time data. Biometrika. 1981; 68: 373–379.